AL HB242

Defines rapid whole genome sequencing as investigation of the entire human genome that yields preliminary results within 5 days and final results within 14 days, including patient-only or duo/trio sequencing with biological parents.

Requires Alabama Medicaid Agency to cover rapid whole genome sequencing for individuals 21 years of age or younger who have complex or acute illness of unknown etiology not caused by environmental exposure, toxic ingestion, responsive infection, or trauma.

Coverage applies only to hospital inpatients in intensive care units (including neonatal intensive care units) or high acuity pediatric units.

Coverage is subject to prior approval or waiver from the Centers for Medicare and Medicaid Services.

Act becomes effective October 1, 2025.