AZ HB2549

Prohibits physicians, osteopathic physicians, naturopathic physicians, nurse practitioners, and physician assistants from dispensing schedule II controlled substances that are opioids, except for implantable devices or opioids used for medication-assisted treatment for substance use disorders.

Establishes a 90 morphine milligram equivalent per day limit for new opioid prescriptions outside health care institutions, with exemptions for cancer patients, trauma, hospice, palliative care, surgical procedures, and medication-assisted treatment.

Requires prescribers exceeding the 90 MME daily limit to consult with a pain management-certified physician or designated opioid assistance and referral call service before issuing higher-dose prescriptions.

Mandates that patients prescribed more than 90 MME per day also receive a prescription for naloxone or another FDA-approved opioid antagonist for overdose treatment.

Applies retroactively to April 25, 2018, and establishes pain management clinic licensure requirements including medical director qualifications and informed consent documentation.