HB 1051 Summary

• Repeals and replaces section 195.017, RSMo, to update Missouri's Schedule I controlled substances list, focusing on synthetic cannabinoids and related compounds.

• Adds numerous synthetic cannabinoid compounds and derivatives to Schedule I, including specific structural classes (indole-based, pyrrole-based, indene-based structures) and named compounds like UR-144, XLR-11, APINACA/AKB48, and PB-22.

• Expands the definition of synthetic cannabinoids to cover compounds derived from multiple core structures with various substitution groups, capturing new analogues designed to circumvent existing prohibitions.

• Adds several other controlled substances to various schedules, including new hallucinogens (2C compounds, 25I/C/B-NBOMe), anabolic steroids (Methasterone, Prostanozol), and depressant/stimulant drugs (Perampanel, Lorcaserin, Alfaxalone, Carisoprodol, Ezogabine).

• Maintains existing requirements for pseudoephedrine/ephedrine sales including age restrictions (18+), pharmacy counter placement, photo ID verification, electronic logging, and submission of sales data to the Department of Health and Senior Services.