H 752: Amend Controlled Substances Act

• Revises the definition of "isomer" in North Carolina's Controlled Substances Act to include structural, geometric, and optical isomers rather than limiting it to optical isomers only.

• Adds new synthetic opioids to Schedule I controlled substances, including Isopropyl-U-47700, U-51754, U-48800, Isotonitazene, Metonitazene, and Brorphine.

• Expands Schedule I fentanyl derivatives provision to apply broadly to any compound structurally derived from fentanyl through substitution or replacement of specified chemical groups, unless specifically excepted or in an FDA-approved pharmaceutical product.

• Adds fentanyl and carfentanil (in addition to existing drugs) to Schedule II offenses, making possession subject to Class I felony penalties when quantity exceeds specified thresholds.

• Adds six anticonvulsant medications (Ezogabine, Lacosamide, Brivaracetam, Pregabalin, Cenobamate, and Lasmiditan) to Schedule III controlled substances.

• Takes effect December 1, 2021 and applies to offenses committed on or after that date.